5. Forensic Chemistry and Toxicology

Analytical Methods — Quiz

Test your understanding of analytical methods with 5 practice questions.

Practice Questions

Question 1

In the Van Deemter equation $H=A+\frac{B}{u}+Cu$, which term represents longitudinal diffusion of the analyte in the mobile phase?

Question 2

Why is chemical derivatization commonly performed prior to gas chromatography analysis of polar forensic compounds such as amino acids?

Question 3

For trace analysis of polycyclic aromatic hydrocarbons (PAHs) by GC–MS, which ionization technique is preferred to maximize the molecular ion signal?

Question 4

During reversed-phase HPLC of a basic drug, significant peak tailing is observed. Which mobile phase modification is most effective at reducing tailing caused by silanol interactions?

Question 5

In electrospray ionization (ESI) for LC–MS, which mobile phase component most directly enhances ionization efficiency of analytes?