5. Forensic Chemistry and Toxicology

Drug Identification — Quiz

Test your understanding of drug identification with 5 practice questions.

Practice Questions

Question 1

In thin-layer chromatography (TLC) used for presumptive screening of illicit drugs, which factor most directly influences the limit of detection (LOD)?

Question 2

In high-resolution accurate mass (HRAM) mass spectrometry for drug identification, what minimum resolving power R (defined as m/Δm) at m/z=200 is generally required to distinguish isobaric interferences?

Question 3

Which microextraction technique involves rapid injection of an extractant into an aqueous sample, forming a cloudy solution of fine droplets to extract drug analytes with minimal solvent use?

Question 4

What is the primary analytical advantage of time-of-flight (TOF) mass analyzers over single-quadrupole analyzers when confirming unknown drug substances?

Question 5

Which statement best meets forensic courtroom standards for reporting a confirmed GC–MS identification of a compound?