2. Antigen Recognition and Processing

T Cell Receptors — Quiz

Test your understanding of t cell receptors with 5 practice questions.

Practice Questions

Question 1

Which enzyme is responsible for opening hairpin coding ends during V(D)J recombination, enabling P-nucleotide addition?

Question 2

What term describes the phenomenon where only one allele of the TCR β chain locus is functionally rearranged and expressed in a single T cell?

Question 3

In V(D)J recombination, what does the '12/23 rule' specify?

Question 4

Which complementarity-determining regions (CDRs) of the TCR are entirely germline-encoded within V gene segments and do not span V(D)J junctions?

Question 5

Which enzyme activated downstream of ZAP-70 generates inositol 1,4,5-trisphosphate (IP₃) and diacylglycerol (DAG) from PIP₂ in the TCR signaling cascade?