4. Host Defense and Pathogens
Antiviral Immunity — Quiz
Test your understanding of antiviral immunity with 5 practice questions.
Practice Questions
Question 1
Which enzyme synthesizes the second messenger cyclic GMP-AMP (cGAMP) upon detection of cytosolic double-stranded DNA?
Question 2
Which adaptor protein in the endoplasmic reticulum membrane binds cyclic GMP-AMP and initiates downstream signaling for type I interferon production?
Question 3
Which endoplasmic reticulum aminopeptidase trims N-terminal residues of proteasome-generated peptides to optimal lengths for MHC class I loading?
Question 4
Which chaperone protein retains the MHC class I heavy chain in the endoplasmic reticulum until it associates with β2-microglobulin?
Question 5
Deficiency of β2-microglobulin would most directly impair which process?