4. Pharmacology and Therapeutics

Infectious Disease — Quiz

Test your understanding of infectious disease with 5 practice questions.

Practice Questions

Question 1

For a drug with an elimination half-life of 6 hours, what fraction of the initial concentration remains after 18 hours?

Question 2

A hospital implements an antimicrobial stewardship intervention that reduces ceftriaxone use from 500 to 350 defined daily doses per month, while Clostridioides difficile infection rates drop from 8 to 5 cases per 10,000 patient-days. What is the relative reduction in CDI rate?

Question 3

Which resistance mechanism confers carbapenem resistance in Pseudomonas aeruginosa through metallo-β-lactamase production?

Question 4

In treating an adult with uncomplicated ESBL-producing Escherichia coli bacteremia, which antibiotic is most appropriate?

Question 5

Which pharmacokinetic/pharmacodynamic index best correlates with vancomycin efficacy and guides dosing to balance efficacy and toxicity?